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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Neuropeptides. 2016 Dec 20;64:75–83. doi: 10.1016/j.npep.2016.12.005

Figure 3. Metabolic analysis of adult female Syn-Cre,Vgfflpflox/flpflox mice fed a standard diet.

Figure 3

Body weight (panel A), body composition including fat mass normalized to body weight (panel B) and lean mass normalized to body weight (panel C), energy expenditure (panel D), respiratory exchange ratio (RER) (panel E), food intake (panel F), and locomotor activity (panel G), were measured in Syn-Cre,Vgfflpflox/flpflox and wild type [(+/+,Vgfflpflox/flpflox) or (Syn-Cre,+/+)] female mice, fed a standard diet. Cohort sizes analyzed in panels A–F are shown above panel C, and in panel G, above panel G.

Panel A. Body weight data was analyzed by ANOVA with Bonferroni post hoc analysis, F (2,24) = 25.67 (P < 0.0001; ***, P < 0.001 vs Syn-Cre,Vgfflpflox/flpflox). Panels B and C. Body fat and lean mass normalized to body weight data were analyzed by ANOVA with Bonferroni post hoc analysis (n.s.). Panel D–G. Energy expenditure, RER, food intake and locomotor activity data were analyzed by ANOVA with Bonferroni’s post hoc analysis between +/+, Vgfflpflox/flpflox and Syn-Cre,Vgfflpflox/flpflox, respectively (**, P<0.01; ***, P<0.001).