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. 2017 Jun 21;7:275. doi: 10.3389/fcimb.2017.00275

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Copyright © 2017 Chen, Rydzewski, Kutzner, Häuslein, Schunder, Wang, Meighen-Berger, Grunow, Eisenreich and Heuner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hypothetical metabolic network of Francisella tularensis. The pathways are predicted on the basis of the genome sequences and earlier biochemical studies (Gyuranecz et al., 2010; Meibom and Charbit, 2010; Raghunathan et al., 2010; Barel et al., 2015). Potential carbon substrates are indicated by red boxes. Major metabolic products are indicated by yellow boxes. Reactions of the glycolytic pathway (EMP) and gluconeogensis (GN) are indicated by red arrows. Reactions of the pentose phosphate pathway (PPP) and the citrate cycle (TCA) are indicated by blue and green arrows, respectively. The interconnection between Gly and Ser includes the glycine cleavage system.