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. 2017 Jun 21;7:272. doi: 10.3389/fcimb.2017.00272

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Copyright © 2017 Sheng, Gao, Wang, Cui, Zhou, Fan, Chen, Wang and An.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome analysis for various pathways in mouse testes at 5 dpi after ZIKV-infection. (A) Gene ontology (GO) analysis for gene upregulated in testes of ZIKV-infected mice at 5 dpi (n = 3). Uninfected mouse testes serve as control (n = 3). The ontology covers three domains: Biological Process (red), Cellular Component (green) and Molecular Function (blue). Fisher's exact test is used for the GO analysis (p < 0.05). (B,C) Transcriptome analysis of selected genes associated with tight junction pathway (B) and integrins (C) in ZIKV-infected testes at 5 dpi. The results were expressed as Fragments Per Kilobase Million (FPKM). Beta-actin (Actb) was used as control.