Table 4. Summary of Characteristics of Patients with Serrated (Hyperplastic) Polyposis in Recent Studies with More Than 10 Cases.
| Author (year) | Nation | Case | Agea at diagnosis (yr) | Sex (M/F) | WHO criterion (I/II/III/I&III) | FU durationa (mo) | Synchronous adenomatous polyp | CRC prevalence | Interval CRC | Extracolonic malignancy |
|---|---|---|---|---|---|---|---|---|---|---|
| Leggett et al. (2001)5 | Australia | 12 | 56.8 | 5/7 | NS | NS | 9 Patients (75.0) | 7 (58.3) | 2 (16.7) | NS |
| Lage et al. (2004)10 | Portugal | 14 | 53.6 | 7/7 | NS | NS | NS | 6 (43.0) | NS | NS |
| Ferrández et al. (2004)21 | USA | 15 | 52.6 | 10/5 | NS | 36.5 | 11 Patients (73.0) | 1 (6.7.0) | 0 | NS |
| Rubio et al. (2006)9 | Sweden | 10 | 61.0 | 8/2 | NS | NS | 8 Patients (80.0) | 7 (70.0) | NS | NS |
| Chow et al. (2006)1 | Australia | 32 | 44.0 | 15/17 | NS | NS | 26 Patients (81.0) | 10 (31.2) | NS | NS |
| Boparai et al. (2010)6 | The Netherlands | 77 | 56.0 | 42/35 | NS | 48 | 273/1,984 Polyps (14.0) | 27 (35.0) | 5 (6.5) | NS |
| Vemulapalli and Rex (2012)22 | USA | 20 | 63.8 | 9/11 | 16/0/2/2 | NS | 19 Patients (95.0) | 5 (25.0) | 0 | NS |
| Edelstein et al. (2013)8 | USA | 44 | 52.5 | 21/23 | 10/0/34/NS | 24.0 | NS | 3 (7.6) | 2 (4.5) | NS |
| Guarinos et al. (2013)23 | Spain | 50 | 49.3 | 27/23 | 15/NS/35/NS | NS | 29 Patients (58.0) | 9 (18.0) | NS | NS |
| Rosty et al. (2013)24 | Australia, USA, Canada, New Zealand | 100 | 50.0 | 42/58 | 12/0/72/16 | NS | 64/80 Patients (80.0) | 39 (42.0) | NS | NS |
| Jasperson et al. (2013)3 | USA | 51 | 51.0 | 24/27 | NS | 61.0 | 42 Patients (82.0) | 7 (13.7) | 1 (1.9) | 12 (23.5) |
| Kalady et al. (2011)25 | USA | 115 | 62.0 | 65/50 | NS | NS | 78 Patients (68.0) | 29 (25.0) | 5 (4.3) | 32 (28) |
| Hazewinkel et al. (2014)13 | The Netherlands | 41 | 56.5 | 24/17 | 6/0/21/14 | 43.0 | 91/575 Polyps (16.0) | 13 (33.0) | 0 | NS |
| Knabe et al. (2014)26 | Germany | 28 | 54.4 | 15/13 | 11/0/17/NS | 21.5 | 39/436 Polyps (8.9) | 2 (7.1) | 0 | 4 (14.3) |
| Hui et al. (2014)27 | USA | 40 | 57.0 | 16/24 | 16/3/32/NS | NS | 25 Patients (63.0) | 16 (40.0) | 0 | NS |
| Elorza et al. (2014)19 | Spain | 23 | 51.0 | 19/4 | 4/0/12/7 | NS | 17 Patients (73.0) | 6 (26.0) | 1 (4.3) | 4 (17.3) |
| Miwata et al. (2013)14 | Japan | 10 | 58.3 | 6/4 | 5/0/5/NS | NS | 24/91 Polyps (26.4) | 3 (30.0) | NS | NS |
| Toyoshima et al. (2015)28 | Japan | 21 | 66.0 | 15/6 | NS | NS | Advanced adenoma and/or CRC in 10 patients (47.6) | NS | NS | |
| Kim et al. (2015)29 | Korea | 11 | 55.6 | 10/1 | 5/0/6/NS | NS | 7 Patients (64.0) | 1 (9.0) | NS | 3 (27.0) |
| Current study | Korea | 30 | 57.4 | 20/10 | 18/0/9/3 | 43.0 | 22 Patients (73.3) | 3 (10.0) | 0 | 4 (13.3) |
Values are presented as number (%).
aAge and follow-up duration are shown as median value. If median value was unavailable, mean value was used instead.
M, male; F, female; WHO, World Health Organization; FU, follow-up; CRC, colorectal cancer; NS, not specified or unknown.