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. 2005 Jan 24;102(5):1584–1589. doi: 10.1073/pnas.0409191102

Table 2. Induction of switch transcripts.

Culture Mouse Id. Genotype Iμ–Cμ transcripts versus GAPDH transcripts* Iγ1–Cγ1 transcripts versus GAPDH transcripts* Percent IgG1 cells
43 CD19-Cre NbnWT/lox-6 24.3 4.1 9.4
I 44 CD19-Cre Nbnlox-6/ins6 20.7 4.1 3.2
42 CD19-Cre Nbnlox-6/lox-6 21.8 4.3 4.3
31 CD19-Cre NbnWT/ins6 14.6 2.4 27.3
II 35 CD19-Cre Nbnlox-6/ins6 19.4 7.2 7.9
33 CD19-Cre Nbnlox-6/lox-6 16.7 4.3 4.2
51 CD19-Cre NbnWT/lox-6 23.3 10.0 4.8
III 52 CD19-Cre Nbnlox-6/ins6 21.9 8.4 2.5
46 CD19-Cre Nbnlox-6/lox-6 22.1 7.5 1.8

Id., identification.

*

RT-PCR analysis was performed on day 2 after LPS/IL-4 activation

IgG1 analysis was performed on day 3 after LPS/IL-4 activation