Figure 6.

Effect of berberine on glutamate-induced DNA damage in N2a and PC12 cells. A: Representative comet images of N2a and PC12 cells from different treatment groups. B: Bar graphs representing the percent of DNA in the comet tail (% tail DNA) of N2a and PC12 cells, as an index for the extent of DNA damage. The data were expressed as means±SEM from three independent experiments. ^###P<0.001 as compared to untreated N2a cells cultured in glutamate condition. ***P<0.001 as compared to untreated PC12 cells cultured in glutamate condition