Table 2.
Solid tumor responses comparisons of HCC patients.
Comparisons | Studies | Groups | Clinical responses (%) | Heterogeneity | RR | 95% CI | P value | |||
---|---|---|---|---|---|---|---|---|---|---|
Chi2 | df | P | I 2 (%) | |||||||
Complete response (CR) | [22, 23, 29, 30, 32, 34–36] | Treatment | 44/442 (10.0) | 3.07 | 7 | 0.88 | 0 | 1.47 | 0.96–2.24 | 0.07 |
Control | 26/406 (6.4) | |||||||||
Partial response (PR) | [20, 22–25, 27, 29, 30, 32, 34–36, 38] | Treatment | 210/610 (34.4) | 9.96 | 12 | 0.62 | 0 | 1.30 | 1.10–1.53 | 0.002 |
Control | 145/551 (26.3) | |||||||||
Stable disease (SD) | [20, 22–25, 27, 29, 30, 32, 34–36, 38] | Treatment | 260/610 (42.6) | 15.89 | 12 | 0.2 | 24 | 0.95 | 0.84–1.08 | 0.47 |
Control | 241/551 (43.7) | |||||||||
Progressive disease (PD) | [20, 22–25, 27, 29, 30, 32, 34–36, 38] | Treatment | 101/610 (16.6) | 9.22 | 12 | 0.68 | 0 | 0.64 | 0.52–0.80 | <0.0001 |
Control | 146/551 (26.5) | |||||||||
Total response rate (tRR) | [20, 22–25, 27, 29, 30, 32, 34–36, 38] | Treatment | 254/610 (41.6) | 13.56 | 12 | 0.33 | 12 | 1.3 | 1.16–1.53 | <0.0001 |
Control | 171/551 (31.0) |