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Characteristics of various selectins.
| Cellular expression | Protein ligands | Rolling velocity of leukocytes | |
|---|---|---|---|
| P-selectin (GMP-140, PADGEM, CD62P) |
Activated endothelium and platelets | PSGL-1 CD24 |
Slow |
|
| |||
| E-Selectin (ELAM-1, CD62E) |
Activated endothelium | PSGL-1 ESL-1 L-Selectin Podocalyxin |
Slow |
|
| |||
| L-Selectin (MEL-14, CD62L) |
Constitutive expression on leukocytes | PSGL-1 GlyCAM-1 MAdCAM-1 CD-34 Podocalyxin |
Fast |
