FIG 4.

AHPND-causing V. parahaemolyticus strains encode mobile T6SS MIX effectors. Mobile genetic elements containing T6SS MIX effectors from the clinical isolate RIMD2210633 and four AHPND strains, including TUMSAT_DE1_S1, NCKU_CV_CHN, FIM-S1708+, and M0605. Components within the mobile elements that are discussed in the text are highlighted with different colors: T6SS mobile MIX effector, blue and cyan; immunity, green; toxin/antitoxin module, orange; genes encoding proteins that mediate DNA rearrangement and mobility upstream of the E/I pair are in red and downstream of the E/I pair are in magenta. The number of omitted genes is shown in parentheses.