FIG 4.

Genes in the proposed pathway for purine biosynthesis and GTP homeostasis were strongly upregulated during biofilm induction in B. cereus. Genes which are involved in the proposed pathway and whose expression was seen to be significantly altered under biofilm induction (in the RNA-seq experiment) are annotated. The fold change in gene expression was also indicated. Significantly increased expression (from 2- to >20-fold) under biofilm induction was seen for genes in green. Significantly decreased expression (from 2- to >10-fold) was seen for genes in orange. Genes in blue indicate insignificant change (<2-fold) in gene expression. Numbers next to the gene name in parentheses represent the fold changes in gene expression.