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. 2017 Jun 21;10(1):20. doi: 10.1186/s40413-017-0153-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Lung Deposition of Beclomethasone diproprionate, Hydrofluoroalkane vs chlorofluorocarbon propellant inhaler [81]. Note the mosaic pattern of areas of low attenuation (representing air – which appears black – trapped behind diseased and functionally closed small airways) juxtaposed with areas of higher attenuation (whiter-appearing, representing lung regions from which the air has been normally expelled through patent airways)