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Comparison of particle size and lung delivery among selected inhaled corticosteroid therapies [82]
| Drug | Formulation | Particle size (microns) | Lung deposition |
|---|---|---|---|
| Fluticasone DPI | Dry powder | 5.4 μm | 15% |
| Fluticasone HFA | Suspension | 2.4 μm | 13–18% |
| BDP- Modulite® | Suspension | 2.6 μm | 36% |
| BDP UF-HFA | Solution | 1.1 μm | >56% |
| Ciclesonide HFA | Solution | 1–2 μm | 52% |
| Flunisolide HFA | Solution | 1.2 μm | 68% |
BDP beclomethasone dipropionate, DPI dry powder inhaler, HFA hydrofluoroalkane, UF ultrafine
