Table 1.
Clinical and demographic characteristics of the parent cohort (n = 2878)
| Alive at discharge | Expired | Total | P value (chi-square test) | Unadjusted OR (95% CI) for inhospital mortality | |
|---|---|---|---|---|---|
| N | 2569 | 309 | 2878 | ||
| Male gender | 1390 (54) | 178 (58) | 1568 (54) | 0.24 | 1.15 (0.91–1.46) |
| Nonwhite race | 536 (21) | 66 (21) | 602 (21) | 0.84 | 1.03 (0.77–1.37) |
| Age (years) | 60.7 ± 18.0 | 67.0 ± 16.8 | 61.4 ± 18.0 | <0.001* | 1.02 (1.01–1.03) |
| Surgical patient type | 1147 (45) | 92 (30) | 1239 (43) | <0.001 | 0.53 (0.41–0.68) |
| Deyo–Charlson Index | <0.001 | ||||
| 0 | 533 (21) | 29 (9) | 562 (20) | 1.00 (Referent) | |
| 1–2 | 628 (24) | 54 (17) | 682 (24) | 1.58 (0.99–2.52) | |
| 3–6 | 566 (22) | 69 (22) | 635 (22) | 2.24 (1.43–3.51) | |
| ≥7 | 842 (33) | 157 (51) | 999 (35) | 3.43 (2.27–5.17) | |
| Sepsis | 241 (9) | 113 (37) | 354 (12) | <0.001 | |
| Pneumonia | 487 (19) | 106 (34) | 593 (21) | <0.001 | 2.23 (1.73–2.88) |
| Noncardiac acute respiratory failure | 169 (7) | 85 (28) | 254 (9) | <0.001 | 5.39 (4.01–7.23) |
| Acute organ failure | <0.001 | ||||
| 0 | 843 (33) | 5 (2) | 848 (29) | 1.00 (Referent) | |
| 1 | 895 (35) | 65 (21) | 960 (33) | 12.25 (4.91–30.56) | |
| 2 | 508 (20) | 73 (24) | 581 (20) | 24.23 (9.73–60.35) | |
| ≥3 | 323 (13) | 166 (54) | 489 (17) | 86.65 (35.27–212.87) | |
| Leukemia or myelodysplastic syndrome | 229 (9) | 53 (17) | 282 (10) | <0.001 | 2.12 (1.53–2.93) |
| Hematocrit | 34.1 ± 7.0 | 30.9 ± 7.0 | 33.8 ± 7.1 | <0.001* | 0.94 (0.92–0.95) |
| Red cell distribution width | 14.8 ± 2.2 | 16.9 ± 2.9 | 15.1 ± 2.4 | <0.001* | 1.32 (1.27–1.38) |
| Chronic kidney disease | 800 (31) | 175 (57) | 975 (34) | <0.001 | 2.89 (2.27–3.67) |
| Acute Organ Failure score | 10.0 ± 4.7 | 15.6 ± 5.0 | 10.6 ± 5.0 | <0.001* | 1.26 (1.23–1.30) |
| NRBCs | <0.001 | ||||
| 0 | 1867 (73) | 101 (33) | 1968 (68) | 1.00 (Referent) | |
| 1–99 | 487 (19) | 83 (27) | 570 (20) | 3.15 (2.32–4.28) | |
| 100–199 | 101 (4) | 43 (14) | 144 (5) | 7.87 (5.23–11.85) | |
| ≥200 | 114 (4) | 82 (27) | 196 (7) | 13.30 (9.39–18.82) | |
| Mortality rate (%) | |||||
| Inhospital | 309 (10.7) | ||||
| 30-day | 392 (13.6) | ||||
| 90-day | 509 (17.7) |
Data presented as n (%) or mean ± SD
*P value determined by ANOVA
CI confidence interval, NRBC nucleated red blood cell, OR odds ratio