Table 3.
Unadjusted and adjusted associations between nucleated red blood cells and mortality (n = 2569)
| Mortality odds ratio (95% CI)a | ||||
|---|---|---|---|---|
| 0/μl NRBCs | 1–100/μl NRBCs | 101–200/μl NRBCs | >200/μl NRBCs | |
| 30-day post discharge mortality | ||||
| Crude | 1.00 (Referent) | 2.34 (1.51—3.62) | 4.21 (2.18—8.11) | 5.47 (3.07—9.74) |
| Adjustedb | 1.00 (Referent) | 2.02 (1.27—3.21) | 3.66 (1.81—7.39) | 4.64 (2.45—8.79) |
| Adjustedc | 1.00 (Referent) | 1.85 (1.16—2.95) | 3.06 (1.50—6.22) | 3.51 (1.82—6.77) |
| Adjustedd | 1.00 (Referent) | 1.86 (1.19—2.90) | 2.90 (1.46—5.74) | 3.66 (1.98—6.75) |
| 90-day post discharge mortality | ||||
| Crude | 1.00 (Referent) | 2.10 (1.50—2.94) | 2.98 (1.69—5.25) | 4.44 (2.74—7.21) |
| Adjustedb | 1.00 (Referent) | 1.77 (1.23—2.54) | 2.51 (1.36—4.62) | 3.72 (2.16—6.39) |
| Adjustedc | 1.00 (Referent) | 1.67 (1.16—2.41) | 2.19 (1.18—4.05) | 3.05 (1.75—5.34) |
| Adjustedd | 1.00 (Referent) | 1.65 (1.16—2.34) | 2.03 (1.12—3.69) | 2.99 (1.78—5.04) |
CI confidence interval, NRBC nucleated red blood cell
aReferent in each case is absence of NRBCs
bModel 1: estimates adjusted for age, gender, race, Deyo–Charlson index, type (surgical vs medical), sepsis and acute organ failure
cModel 2: estimates adjusted for age, gender, race, Deyo-Charlson index, type (surgical vs medical), sepsis, acute organ failure, hematocrit < 30, leukemia or myelodysplastic syndrome
dModel 3: estimates adjusted for gender and the Acute Organ Failure score