Table 1.

Treatment effects of two 7-years old DMD boys under eplerenone and glucocorticoid treatment, respectively. There is a decrease of the 23Na IR signal and the muscular sodium concentration following both eplerenone and glucocorticoid treatment. The reduction of muscular water content (measured by the DIXON water mapping) was more pronounced in the boy with eplerenone treatment (especially in deep posterior muscle compartment and peroneus muscle compartment). A slighter change has been found for glucocorticoid treatment. Both the degree of fatty degeneration and the fat fraction (measured within the soleus muscle) remains constant over the 6 months' period.