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. 2017 Jun 20;112(12):2683–2695. doi: 10.1016/j.bpj.2017.05.012

Figure 2.

Figure 2

Cell deformation is shown in response to (A) apical, (B) basal, and (C) lateral modulations. The relationship between the changes in apical length and the changes in basal (top) and lateral (bottom) lengths was analyzed for columnar (I; g = 0.25), cuboidal (II; g = 1.00), and squamous (III; g = 1.75) cells. The data points were obtained from the sheets shown in the blue and green boxes in Fig. 1. The dashed lines were obtained from the theoretical analysis of cell deformation (see (A10), (A11), (A9) in the Appendix A) and were highlighted in magenta (otherwise black) when the slope changes sign with varying cell aspect ratio g. The color bars indicate the relative deviation of parameter values from those of the flat sheet. The characteristic deformation of type-I and type-III cells (the circled crosses) are displayed in Fig. 3. To see this figure in color, go online.