Table 2.
Relationship between GS28 expression and clinicopathological parameters in CRC patients
| Parameter | GS28 expression (n = 214a) | P value | |
|---|---|---|---|
| nuclear predominant | non-nuclear predominant | ||
| Sex | 0.987 | ||
| Male | 16 | 116 | |
| Female | 10 | 72 | |
| Age | 0.452 | ||
| ≤ 55 years | 5 | 49 | |
| > 55 years | 21 | 139 | |
| Tumour stage | 0.045* | ||
| T1, T2 or T3 | 16 | 148 | |
| T4 | 10 | 40 | |
| Nodal stage | 0.654 | ||
| N0 or N1 | 18 | 138 | |
| N2 | 8 | 50 | |
| Metastasis | 0.102 | ||
| M0 | 22 | 176 | |
| M1 | 4 | 12 | |
| Lymphatic invasion | 0.738 | ||
| Absent | 10 | 66 | |
| Present | 16 | 122 | |
| Vascular invasion | 0.822 | ||
| Absent | 23 | 169 | |
| Present | 3 | 19 | |
| Perineural invasion | 0.064 | ||
| Absent | 14 | 136 | |
| Present | 12 | 52 | |
| Differentiation | 0.644 | ||
| Well-to-moderate | 24 | 178 | |
| Poor | 2 | 10 | |
| Site | 0.764 | ||
| Right colon | 7 | 56 | |
| Left colon or rectum | 19 | 132 | |
aOne case with GS28 non-immunoreactivity is included in the non-nuclear predominant subgroup.
* Statistically significant
CRC: colorectal cancer