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DEFs for TiO2-NPs in PRESAGE® dosimeter studies and in vitro cell studies at 80 % cell survival.
| Energy | Study & test type | TiO2-NP concentration (mM) | |||
|---|---|---|---|---|---|
| 0.5 mM | 1 mM | 4 mM | |||
| 80 kV | PRESAGE® | 1.12 | 1.40 | ------- | |
| HaCaT | MTS | 1.21 | 1.57 | 1.70 | |
| Clonogenic | 1.17 | 1.34 | 1.56 | ||
| DU145 | MTS | 1.27 | 1.45 | 1.77 | |
| Clonogenic | 1.21 | 1.40 | 1.68 | ||
| 6 MV | PRESAGE® | 1.04 | 1.03 | ------- | |
| HaCaT | MTS | 1.09 | 1.19 | 1.50 | |
| Clonogenic | 1.13 | 1.18 | 1.37 | ||
| DU145 | MTS | 1.14 | 1.26 | 1.67 | |
| Clonogenic | 1.10 | 1.19 | 1.43 | ||
