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. 2017 Apr 10;7(7):1875–1889. doi: 10.7150/thno.18985

Figure 2.

Figure 2

Dual-stimulus-responsive biodegradation and drug release of DOX-EGF-SA-AuNPs in acidic and redox environments. (A) Representative TEM images of DOX-EGF-SA-AuNPs with 10 mM GSH at different time points (5 min, 30 min, 4 h, 24 h, 48 h and 72 h). Scale bars, 200 nm. (B) Fluorescence intensities of DOX released from DOX-EGF-SA-AuNPs at different pH levels (4.5 and 7.4) at different time intervals. (C) Fluorescence intensities of DOX released from DOX-EGF-SA-AuNPs with GSH (10 mM) at pH 4.5 and 7.4 at different time points.