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In vivo antitumor activity and toxicology evaluation in situ brain tumor model. (A) Survival curve of U87 brain tumor-bearing mice. Mice were treated at a DOX dose of 1.5 mg/kg via intravenous administration on days 8 and 15 after tumor inoculation. Error bars indicate s.d. (n=6). (B) The body weight variations of U87 tumor-bearing mice during treatment (n=6).
