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. 2017 Jun 15;11:1753–1766. doi: 10.2147/DDDT.S132488

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© 2017 Ke et al. This work is published and licensed by Dove Medical Press Limited

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CTS suppressed the growth of HCCC-9810 cells in athymic nude mice.

Notes: HCCC-9810 cells were subcutaneously injected into the right axilla of the nude mice. The mice were then administered 0.2 mL of vehicle (10% DMSO and 90% PBS) or CTS (0, 10, and 25 mg/kg) intraperitoneally every 2 days for up to 4 weeks. (A) Photo of 6 representative tumors excised from the animals of each group are presented to show the sizes of the resulting tumors. (B) Tumors were excised from the animals and weighed. (C) Tumor dimensions were periodically measured using calipers over the 4 weeks. Significant differences from the control are indicated by *P<0.05 and **P<0.01.

Abbreviations: CTS, cryptotanshinone; DMSO, dimethyl sulfoxide.