Table 4.

Odds ratios for associations between serum lipid levels and presence and extent of baseline acute prostate inflammation in REDUCE

	Presence of acute inflammation			Extent of acute inflammation
	None	Any		None	Moderate;	< 20% of cores	Severe;	≥ 20% of cores
	n	n	OR (95% CI)	n	n	OR (95% CI)	n	OR (95% CI)
Total cholesterol
<200 mg/dl	1,067	195	1	1,067	125	1	67	1
200–239 mg/dl	3,364	599	1.06 (0.89–1.27)	3,364	398	1.08 (0.87–1.34)	195	1.04 (0.78–1.39)
≥240 mg/dl	1,219	211	1.09 (0.87–1.35)	1,219	150	1.18 (0.91–1.52)	61	0.96 (0.67–1.39)
p-trend			0.669			0.313		0.655
LDL
<130 mg/dl	2,802	522	1	2,802	352	1	165	1
130–159 mg/dl	1,645	275	0.97 (0.82–1.15)	1,645	181	0.95 (0.78–1.16)	91	1.00 (0.76–1.32)
≥160 mg/dl	1,203	208	1.04 (0.86–1.25)	1,203	140	1.04 (0.83–1.29)	67	1.07 (0.78–1.46)
p-trend			0.556			0.584		0.670
HDL
<40 mg/dl	1,105	219	1	1,105	139	1	79	1
40–59 mg/dl	3,460	622	0.92 (0.78–1.09)	3,460	419	0.97 (0.79–1.19)	196	0.81 (0.62–1.07)
≥60 mg/dl	1,085	164	0.79 (0.63–0.99)	1,085	115	0.86 (0.66–1.13)	48	0.66 (0.45–0.97)
p-trend			0.071			0.248		0.120
Triglyceride
<150 mg/dl	3,639	640	1	3,639	418	1	215	1
150–199 mg/dl	1,054	181	1.00 (0.84–1.20)	1,054	126	1.08 (0.87–1.34)	54	0.87 (0.64–1.19)
≥200 mg/dl	957	184	1.11 (0.92–1.33)	957	129	1.20 (0.97–1.49)	54	0.95 (0.69–1.30)
p-trend			0.268			0.118		0.884

ORs were adjusted for age at baseline (continuous), race (white, non-white), geographic region (North America, Europe, other), BMI (continuous, log-transformed), smoking status (never, former, current), statin use (no, yes), and NSAID use (no, yes)