Table 5.

Odds ratios for associations between statin use and presence and extent of baseline prostate inflammation in REDUCE

	Presence of chronic inflammation			Extent of chronic inflammation
	None	Any		None	Moderate;	< 20% of cores	Severe;	≥ 20% of cores
	n	n	OR (95% CI)	n	n	OR (95% CI)	n	OR (95% CI)
Statin use
No	1,212	4,226	1	1,212	1,592	1	2,582	1
Yes	292	925	0.81 (0.69–0.95)	292	346	0.82 (0.68–0.99)	570	0.80 (0.68–0.95)

	Presence of acute inflammation			Extent of acute inflammation
	None	Any		None	Moderate;	< 20% of cores	Severe;	≥ 20% of cores
	n	n	OR (95% CI)	n	n	OR (95% CI)	n	OR (95% CI)
Statin use
No	4,632	806	1	4,632	530	1	269	1
Yes	1,018	199	0.97 (0.81–1.17)	1,018	143	1.11 (0.90–1.38)	54	0.73 (0.53–1.00)

ORs were adjusted for age at baseline (continuous), race (white, non-white), geographic region (North America, Europe, other), BMI (continuous, log-transformed), smoking status (never, former, current), NSAID use (yes, no)