Table 2.

Genetic Mutations and Syndromes Associated With Increased Risk for Pancreatic Cancer

Genetic Mutations	Family Syndromes
BRCA1/BRCA2	Hereditary breast and ovarian cancer syndrome
PALB2	Hereditary syndrome related to PALB2 mutation
MLH1, MSH2, MSH6, PMS2	Lynch syndrome
TP53	Li-Fraumeni syndrome
CDKN2A/p16	Familial atypical multiple mole melanoma syndrome
STK11	Peutz-Jeghers syndrome
PRSS1	Hereditary pancreatitis syndrome