Table 1. Comparison of baseline characteristics between acute liver failure patients and healthy participants.
Characteristic | Normal reference | Control group (n=160) | Case group (n=138) | χ2/t | P |
---|---|---|---|---|---|
Gender (male/female) | 129/31 | 112/26 | 0.117 | 0.907 | |
Age (years) | 36.82±5.32 | 37.33±4.94 | 0.853 | 0.394 | |
BMI (kg/m2) | 18.5–24.99 | 24.37±3.74 | 25.06±3.59 | 1.618 | 0.107 |
GPT (U/L) | 0–40 | 33.87±5.22 | 119.86±19.83 | 52.78 | <0.001 |
GOT (U/L) | 8–40 | 28.69±2.48 | 151.07±18.81 | 81.50 | <0.001 |
TB (µmol/L) | 3.4–17.1 | 12.59±2.34 | 330.34±35.55 | 112.80 | <0.001 |
Blood ammonia (µmol/L) | 20–60 | 55.06±8.07 | 87.40±9.81 | 31.22 | <0.001 |
LA (mmol/L) | 0.5–1.7 | 1.15±0.46 | 4.96±2.39 | 19.75 | <0.001 |
Data are reported as mean±SD. BMI: body mass index; GPT: glutamic pyruvic transaminase; GOT: glutamic oxaloacetic transaminase; TB: total bilirubin; LA: lactic acid. The chi-square test or the t-test was used for statistical analysis.