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. 2017 May 15;50(6):e5954. doi: 10.1590/1414-431X20175954

Table 3. Effect of salvianolic acid B (SAB) on the activities of renal inflammatory markers in experimental groups.

Group NF-p65 (pg/mg protein) IL-1β (ng/mg protein) IL-6 (pg/mg protein) TNF-α (ng/mg protein)
Sham control 95.82 ± 9.12 81.55 ± 9.81 91.39 ± 8.67 98.86 ± 10.32
IR 211.35 ± 23.93a ** 198.34 ± 16.13a ** 232.38 ± 31.24a ** 272.13 ± 21.45a **
SAB 20 + IR 125.85 ± 10.01b ** 121.83 ± 12.93b ** 136.67 ± 12.62b ** 167.13 ± 18.23b **
SAB 40 + IR 101.45 ± 12.83b ** c * 96.94 ± 9.56b ** c * 112.43 ± 11.73b ** c * 130.11 ± 12.44b * c *

Data are reported as means±SD for 10 rats in each group.

*

P<0.05,

**

P<0.01

a

IR group compared to the sham control group;

b

treatment groups (SAB 20 and 40 mg·kg−1·day−1) compared to the IR insulted group;

c

SAB 40 group compared to the SAB 20 group (ANOVA). IR: ischemic reperfusion; NF-p65: nuclear factor p65 subunit; IL-1β: interleukin 1β; IL-6: interleukin 6; TNF-α: tumor necrotic factor α.