Figure 2. Knockdown of HDAC2 reduced cell viability in HCT116 cells. Cells were infected with shRNA-NC or HDAC2 shRNA. A and B, Protein expression of HDAC2 in infected cells. C, Cell viability of infected cells. Data are reported as the mean±SD of 3 independent experiments. *P<0.05; **P<0.01; ***P<0.001 (two-tailed unpaired t-test). HDAC2: histone deacetylase 2; HDAC2 shRNA: short hairpin RNA targeting HDAC2; shRNA-NC: negative control of HDAC2 shRNA; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.
