Table 4.
Comparison of baseline demographics, clinical characteristics, and laboratory data (median and interquartile range with 25th and 75th percentiles for continuous variables and frequency and proportion for categorical variables) for patients with and without repeat FMT.
No repeat FMT (N = 33) | Repeat FMT (N = 24) | P Value | |
---|---|---|---|
Age (year) | 72 (58 – 79) | 74 (63 – 79) | 0.71 |
Women | 17 (51.5%) | 17 (70.8%) | 0.178 |
Severe/complicated CDI | 21 (63.6%) | 17 (70.8%) | 0.777 |
WBC | 15.1 (11.1 – 22) | 22.6 (16.2 – 27.7) | 0.02 |
Albumin | 2.6 (2.3 – 2.8) | 2.3 (2 – 2.6) | 0.028 |
Number of CDI episodes | 3 (2 – 4) | 3 (2 – 4) | 0.699 |
ICU admission | 8 (24.2%) | 11 (45.8%) | 0.099 |
Presence of toxic megacolon | 3 (9.1%) | 6 (25%) | 0.146 |
Acute renal failure | 15 (45.5%) | 11 (45.8%) | 1 |
Pseudomembranes at first FMT | 15 (45.5%) | 20 (83.3%) | 0.006 |
Charlson co-morbidity index | 6 (4 – 8) | 6 (5 – 7) | 0.806 |
Immunosuppression | 5 (15.2%) | 5 (20.8%) | 0.728 |
Use of non-anti CDI antibiotics during admission | 11 (33.3%) | 16 (66.7%) | 0.017 |
Abdominal pain | 25 (75.8%) | 16 (66.7%) | 0.554 |
Shock | 5 (15.2%) | 7 (29.2%) | 0.324 |
Vasopressor use | 6 (18.2%) | 5 (20.8%) | 1 |
Mechanical ventilation | 1 (3%) | 3 (12.5%) | 0.3 |
Dialysis | 5 (15.2%) | 1 (4.2%) | 0.385 |
Frozen stool | 17 (51.5%) | 11 (45.8%) | 0.79 |
Use of stool from universal donor | 26 (78.8%) | 20 (83.3%) | 0.745 |