2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

. Author manuscript; available in PMC: 2017 Sep 21.

Published in final edited form as: Circulation. 2016 Nov 13;135(12):e686–e725. doi: 10.1161/CIR.0000000000000470


Recommendations for Cilostazol, Pentoxifylline, and Chelation Therapy

COR	LOE	Recommendations

I	A	Cilostazol is an effective therapy to improve symptoms and increase walking distance in patients with claudication.^119,163

III: No Benefit	B-R	Pentoxifylline is not effective for treatment of claudication.^119,164

III: No Benefit	B-R	Chelation therapy (eg, ethylenediaminetetraacetic acid) is not beneficial for treatment of claudication.¹⁶⁵