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. Author manuscript; available in PMC: 2017 Jun 21.
Published in final edited form as: Nature. 2016 Jul 27;536(7614):76–80. doi: 10.1038/nature18944

Extended Data Figure 10. Elimination of phase delay by DAMGO and a diversity of postinspiratory waveforms in vivo.

Extended Data Figure 10

a, Injection of 5 μM DAMGO into PiCo eliminates the phase delay elicited by photostimulation of PiCo in Chat-cre;Ai27 mice. A representative experiment showing cVN and XII recordings during a 200 ms light pulse before and after injection of PiCo with DAMGO (left; gray bars = expected phase, purple bars = inspiratory phase delay) and the average inspiratory phase delay (right) (mean ± s.e.m., two-tailed paired t-test, **P<0.01; n=6). b, A diversity of postinspiratory vagal waveforms were recorded in vivo. Five examples of cVN (black) and XII (purple) recordings (overlaid) show that postinspiratory activity can vary from large decrementing patterns to small short bursts, potentially representing the neural basis for a variety of postinspiratory behaviors.