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. Author manuscript; available in PMC: 2017 Jun 21.
Published in final edited form as: Biochemistry. 2016 Apr 4;55(15):2197–2213. doi: 10.1021/acs.biochem.5b01354

Figure 2.

Figure 2

Stabilization of gp120 monomers caused by deletions of variable loops as detected by H/D exchange. (A) Deuterium exchange for FL, ΔV3, ΔV1/V2, Coree, and FL+sCD4 at 1 min plotted on the heat map (from left to right). (B) Differences in deuterium exchange between FL and ΔV3, FL and ΔV1/V2, FL and Coree, and FL and FL+sCD4 at 1 min plotted on the heat map. The degrees of change between the two proteins are colored from white (<20% difference) to orange (20–50% difference) to red (>50% difference).