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. 2017 Jun 21;12(6):e0179834. doi: 10.1371/journal.pone.0179834

Table 3. Univariate correlations between kisspeptin concentration and anthropometric and metabolic variables.

Whole study group Subjects with NGT (N = 159) Subjects with IGT (N = 102)
Kisspeptin Kisspeptin Kisspeptin
r P r P r P
Age (years) 0.18 0.007 0.17 0.01 0.07 0.22
BMI (kg/m2) -0.12 0.04 -0.13 0.04 -0.11 0.11
Waist circumference (cm) -0.12 0.04 -0.10 0.10 -0.13 0.08
Systolic blood pressure (mmHg) 0.09 0.09 0.07 0.16 0.05 0.30
Diastolic blood pressure (mmHg) 0.17 0.007 0.15 0.02 0.10 0.16
Total cholesterol (mg/dl) 0.08 0.10 0.03 0.36 0.12 0.11
HDL cholesterol (mg/dl) -0.01 0.48 -0.06 0.19 -0.13 0.09
Triglycerides (mg/dl) 0.07 0.15 0.10 0.09 0.06 0.29
Fasting glucose (mg/dl) 0.07 0.14 0.05 0.27 0.01 0.49
2-h glucose (mg/dl) 0.12 0.03 0.12 0.06 0.01 0.49
Fasting insulin (μU/ml) -0.10 0.06 -0.16 0.02 -0.01 0.37
IGF-1(ng/ml) -0.09 0.10 -0.10 0.11 -0.04 0.34
Matsuda Insulin Sensitivity index (mg x L2 x mmol-1 x mU-1 x min-1) 0.01 0.41 0.05 0.23 0.01 0.48
Insulinogenic index (ΔIns30/ΔGluc30)(μU/ml per mg/dl) -0.24 <0.0001 -0.25 0.001 -0.17 0.04
Stumvoll 1st phase index (pmol/l) -0.21 0.001 -0.22 0.003 -0.16 0.05
Stumvoll 2nd phase index (pmol/l) -0.20 0.002 -0.21 0.004 -0.15 0.05
CIR30 -0.23 <0.0001 -0.25 0.001 -0.16 0.05
Disposition index (ΔIns30/ΔGluc30 x Matsuda index) -0.20 0.002 -0.22 0.003 -0.17 0.05

NGT = normal glucose tolerance; IGT = impaired glucose tolerance; BMI = body mass index; HDL = high density lipoprotein; IGF-1 = insulin-like growth factor 1; CIR30 = corrected insulin response.