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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Neuropharmacology. 2017 Feb 1;122:22–35. doi: 10.1016/j.neuropharm.2017.01.032

Figure 2. The 50% knockdown time (K50) is a behavioral endpoint that occurs at a fixed ethanol concentration even when environmental conditions produce extreme differences in K50 time.

Figure 2

The internal ethanol concentration of 39 groups of 10 flies quantified at the time when half of the flies in each group succumbed to ethanol sedation. While the K50 time differed greatly, the internal ethanol remains fixed within a narrow range around 111 mM +/− 2.3 (Pohl et al, 2013 used with permission).