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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Mol Carcinog. 2017 Mar 6;56(7):1789–1797. doi: 10.1002/mc.22636

Figure 4.

Figure 4

The role of PHB in UVB-induced apoptosis in HaCaT cells. (a) HaCaT cells were transiently transfected with scrambled siRNA or PHB siRNA. The cells without transfection were used as control. The levels of PHB, p-ERK, ERK, p-Akt, Akt, and β-actin in the transfected cells with or without UVB (50 mJ/cm2, 6 h) were assessed by western blotting analysis. The data represents three experiments. (b) The levels of p-Akt, Akt, caspase-3, and β-actin in Akt I (1 μM) and/ or UVB (50 mJ/cm2, 6 h) treated cells were assessed by western blotting analysis. The data represents three experiments.