(A) Shows time course of LDH release in acute hippocampal slices from rat and seAGS exposed to ISS, pH 6.3 (n= 3) or aCSF, pH 7.3 (n=3). *p< 0.05 rat aCSF vs. rat ISS (pH 7.4), +p< 0.05 rat ISS vs seAGS ISS (pH 6.3). (B) Shows time course of LDH release exposed to low pH 6.3 (n= 7) or aCSF, pH 7.3 (n=7). *p< 0.05 rat aCSF pH 7.4 vs. rat aCSF pH 6.3, +p< 0.05 rat aCSF pH 6.3 vs seAGS aCSF pH 6.3. Grey bar indicates treatment period. Means ± SEM.