. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: Fam Cancer. 2017 Jul;16(3):357–361. doi: 10.1007/s10689-016-9960-y

Table 1.

Clinical and pathologic characteristics of probands positive for the MSH2 inversion

	Sex	Cancer diagnosis	Age at diagnosis (y)	MSI analysis	IHC	Amsterdam II criteria
1	Male	Ascending colon adenocarcinoma	46	ND	Absent MSH2/MSH6	No

2	Female	Endometrial cancer	41	MSI-H	Absent	No
		Ascending colon adenocarcinoma	55		MSH2/MSH6
		Transverse colon adenocarcinoma	56

3	Male	Transverse colon adenocarcinoma	37	ND	Absent MSH2/MSH6	Yes

4	Male	Sebaceous Adenoma	54	ND	Absent MSH2/MSH6	No

MSI microsatellite instability; ND not done; MSI-H microsatellite instability-high; IHC immunohistochemistry