Table 1.
Brain regions with atypical functional connectivity with the periaqueductal gray in rats induced by dural inflammatory stimulation.
| Cluster or region of interest | Coordinates of peak(s) voxel (x, y, z) | Peak T value | Effect direction |
|---|---|---|---|
| Cingulate gyrus | 0.67, 0.79, −1.08 | 5.18 | IS > Control |
| Prefrontal cortex (prefrontal cortex, anterior cingulate cortex, medial prefrontal cortex) | 0.66, 1.12, 0.12 | 3.66 | IS > Control |
| Motor cortex | 0.80, 0.90, −0.60 | 7.61 | IS > Control |
| Basal ganglia (caudate putamen, striatum) | 2.53, 5.49, −0.12 | 7.30 | Control > IS |
| Dorsal thalamus, lateral nucleus group | 2.28, 5.60, −1.56 | 4.27 | Control > IS |
| Internal capsule | 2.28, 5.55, −1.08 | 6.54 | Control > IS |
| Prelimbic cortex | −0.35, 2.10, 4.92 | 4.38 | Control > IS |
Regions with changes in functional connectivity with the periaqueductal gray were found in rats induced by subcranial (supradural) infusion of inflammatory soup compared with saline-treated control rats. The coordinates according to Paxinos and Watson40 are given in mm.