Table 2.
Main effect, interaction and Pearson correlation terms relating FA in a priori white matter tracts and processing speed composite score to diagnostic group and age.
| Main Effect of Group | Main Effect of Age | Group by Age Interaction | Group-wise correlations with age | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BD | HC | |||||||||||||
| β | t | p | rsp2 | β | t | p | rsp2 | β | t | p | rsp2 | r (p) | ||
| Right UF FA | −0.08 | −2.59 | 0.01* | 0.09 | −.001 | −2.58 | 0.01* | 0.10 | 0.002 | 2.83 | 0.006* | 0.12 | −.40 (.02*) | .21 (.21) |
| Left UF FA | 0.02 | 0.63 | 0.53 | 0.01 | 0.000 | −0.81 | 0.42 | 0.01 | 0.000 | −0.21 | 0.73 | 0.001 | −.14 (.42) | − 24 (.14) |
| Right SLF FA | −0.01 | −0.52 | 0.61 | 0.004 | −0.001 | −1.78 | 0.08 | 0.04 | 0.000 | 0.57 | 0.57 | 0.005 | −.35 (.05*) | −.18 (.28) |
| Left SLF FA | 0.000 | 0.00 | 0.99 | 0.00 | −0.00 | −1.99 | 0.05 | 0.05 | 0.000 | .146 | 0.88 | 0.00 | −.40 (.02*) | −.30 (.07) |
| PS | 12.44 | 1.23 | 0.22 | 0.02 | 0.51 | 3.24 | 0.00** | 0.13 | −0.41 | −1.96 | 0.05* | 0.05 | .41 (.02*) | .21 (.21) |
Note:
p ≤ .05
p ≤ .001;
FA = fractional anisotropy; UF = uncinate fasciculus; SLF = superior longitudinal fasciculus; PS = processing speed; BD = bipolar disorder; HC = healthy controls; β = unstandardized beta coefficient; t = t-statistic; r = Pearson correlation coefficient; rsp2 = semi-partial correlation squared; Degrees of freedom for regression = 3; Degrees of freedom for correlation = 32 (BD group) and 37 (HC group).