Figure 6.
Protein expression of mitochondrial complexes and their activity in hypertrophic rat heart and effect of toll-like receptor 4 (TLR4) modulation. (A) Protein expression of mitochondrial complexes, (B) fold change in expression of mitochondrial complexes (I–V) in all study groups. Whole gel stain was used for loading control, (C) mitochondrial metabolic enzymes activity in hypertrophic rat heart and effect of TLR4 modulation. (I) complex-I: NADH dehydrogenase, (II) complex-II: succinate dehydrogenase, (III) citrate synthase (IV) β-hydroxy acylcoA dehydrogenase. Data shown as mean ± SEM (N = 4 for activity and N = 3 for western blot) *p < 0.05, **p < 0.01 vs Con; #p < 0.05, ##p < 0.01 vs ISO groups.