Table 3.
The p-values and the mean z-score between-group differences (listed inside the parenthesis) obtained from both the volume and the shape analysis of contrasts between the ε4 carriers and non-carriers within the entire AD group, the Young-Old AD (AD-YO) group, and the Very-Old AD (AD-VO) group respectively. Bold italic typesetting indicates that the group difference in that comparison is statistically significant after multiple comparison correction at a level of p = 0.0125. For the mean z-score difference, the more positive, the more atrophy there is in the latter group, and the more negative, the more atrophy there is in the former group.
| AD-e3 vs. AD-e4 | AD-YO-e3 vs. AD-YO-e4 | AD-VO-e3 vs. AD-VO-e4 | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| volume | shape | volume | shape | volume | shape | |
| lhi | 0.0134 (0.526) | 0.2530 (0.279) | 0.0098 (0.897) | 0.0895 (0.460) | 0.2085 (0.074) | 0.2185 (0.234) |
| rhi | 0.0050 (0.556) | 0.0235 (0.319) | 0.0000 (1.111) | 0.0012 (0.644) | 0.9795 (−0.235) | 0.9995 (−0.057) |
| lam | 0.1580 (0.250) | 0.0017 (0.198) | 0.0101 (0.616) | 0.0026 (0.478) | 0.7680 (−0.166) | 0.6695 (0.053) |
| ram | 0.0583 (0.310) | 0.0391 (0.295) | 0.0002 (0.887) | 0.0007 (0.754) | 0.4165 (−0.542) | 0.4240 (−0.226) |
Key: lhi – left hippocampus, rhi – right hippocampus, lam – left amygdala, ram – right amygdala.