Table 5.
The p-values and the mean z-score between-group differences (listed inside the parenthesis) obtained from both the volume and the shape analysis of contrasts between the ε4 carriers and non-carriers within respectively the entire MCI converter (MCI-C) group, the Young-Old MCI-C (MCI-C-YO) group, and the Very-Old MCI-C (MCI-C-VO) group. Bold italic typesetting indicates the group difference in that comparison is statistically significant after multiple comparison correction at a level of p = 0.0125. For the mean z-score difference, the more positive, the more atrophy there is in the latter group, and the more negative, the more atrophy there is in the former group.
MCI-C-e3 vs. MCI-C-e4 | MCI-C-YO-e3 vs. MCI-C-YO-e4 | MCI-C-VO-e3 vs. MCI-C-VO-e4 | ||||
---|---|---|---|---|---|---|
| ||||||
volume | shape | volume | shape | volume | shape | |
lhi | 0.0148 (0.511) | 0.4820 (0.192) | 0.0084 (0.863) | 0.0750 (0.334) | 0.5135 (0.282) | 0.9490 (0.052) |
rhi | 0.0043 (0.630) | 0.0038 (0.405) | 0.0374 (0.695) | 0.0295 (0.347) | 0.1265 (0.669) | 0.3395 (0.454) |
lam | 0.0243 (0.455) | 0.1425 (0.318) | 0.0965 (0.481) | 0.0895 (0.322) | 0.3040 (0.672) | 0.7055 (0.212) |
ram | 0.0003 (0.696) | 0.0059 (0.555) | 0.0757 (0.548) | 0.0840 (0.396) | 0.0704 (0.811) | 0.1235 (0.628) |
Key: lhi – left hippocampus, rhi – right hippocampus, lam – left amygdala, ram – right amygdala.