Table 1.
subject characteristics, neuropsychological scores for RLS patients and controls, and p-value for group comparision.
| RLS (n = 33) |
Control (n = 29) |
Group difference (P-value) |
|
|---|---|---|---|
| Age | 65.21 ± 1.78 | 64.41 ± 1.60 | |
| First appointment (In the morning %) |
57.6% | 62.1% | |
| Sex (Female %) | 75.8% | 75.9% | |
| RLS medication | Levodopa, Pramipexol, Ropinirol, Rotigotin | ||
| IRLS | 26.42 ± 1.24 (severe RLS symptoms) |
||
| Sleep duration (hour) | 5.61 ± 0.25 | 7.03 ± 0.15 | p < 0.001 |
| Sleep quality | 0.00 ± 0.10 | 0.67 ± 0.09 | p < 0.001 |
| BDI | 11.14 ± 1.43 | 4.13 ± 0.71 | p < 0.001 |
| FSMC (total) | 52.39 ± 3.02 | 31.93 ± 2.00 | p < 0.001 |
| FSMC (cognitive) | 26.31 ± 1.54 | 15.07 ± 0.96 | p < 0.001 |
| FSMC (motoric) | 26.09 ± 1.65 | 16.86 ± 1.10 | p < 0.001 |
| MEQ | 60.44 ± 1.38 | 58.68 ± 2.25 | p = 0.494 |
| Stroop word (msec) | 14.90 ± 0.46 | 14.86 ± 0.49 | p = 0.957 |
| Stroop color (msec) | 20.84 ± 0.56 | 21.03 ± 0.60 | p = 0.819 |
| Stroop conflict (msec) | 41.49 ± 2.24 | 37.10 ± 2.40 | p = 0.186 |
| d2-R | 123.00 ± 5.33 | 141.01 ± 5.65 | p = 0.024 |
| Benton | 12.45 ± 0.25 | 12.56 ± 0.31 | p = 0.797 |
| VLMT-reproduction (working memory) |
11.06 ± 0.35 | 12.01 ± 0.37 | p = 0.067 |
| VLMT-reproduction (long-term memory) |
3.21 ± 0.32 | 3.15 ± 0.35 | p = 0.903 |
| VLMT-reorganization (long-term memory) |
12.46 ± 0.32 | 12.97 ± 0.35 | p = 0.287 |
| VLMT-reproduction (vulnerability to interference) |
3.60 ± 0.35 | 3.23 ± 0.37 | p = 0.472 |
IRLS: International RLS Rating Scale; BDI: Beck Depression Inventory; FSMC: Fatigue Scale for Motor and Cognitive functions; MEQ: Morningness-Eveningness Questionaire. Lower scores represent greater eveningness and higher scores represent greater morningness; VLMT: Verbal Learning and Memory retention Test.