Table 4.
Multivariate Cox regression survival analysis for all patients undergoing surgery (n = 125).
| Variables | OS | DFS | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| NLR (≥2.43 versus <2.43) | 2.571 | 0.968–6.832 | 0.058 | 2.229 | 1.012–4.911 | 0.047 |
| CEA (≥5 ng/mL versus <5 ng/mL) | 3.713 | 1.396–9.873 | 0.009 | 3.652 | 1.630–8.179 | 0.002 |
| COCN (0,1, 2) | 3.106 | 1.576–6.123 | 0.001 | 3.139 | 1.800–5.472 | <0.001 |
| Tumor stage | 3.384 | 0.972–11.778 | 0.055 | 2.449 | 0.978–6.131 | 0.056 |
NLR = neutrophil-to-lymphocyte ratio; CEA = carcinoembryonic antigen; COCN = combination of CEA and NLR; HR = hazard ratio; OS = overall survival; DFS = disease-free survival.