FIG. 7.

trans activation of the hTFB1M promoter and its mutated derivatives by PGC-1α and PRC. (A) The hTFB1M promoter deletions shown in Fig. 5 were assayed for trans activation by PGC-1α (gray bars) and PRC (black bars) by cotransfection with vectors expressing each coactivator. Values are the average fold activation for three separate determinations ± standard error measured relative to the pSVSport negative control. (B) Same as panel A except that the indicated point mutations were assayed for trans activation by the coactivators.