Table 3.
Univariate and multivariate analyses of prognostic factors for overall survival in liver cancer patients.
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| HR | p > |z| | 95% CI | HR | p > |z| | 95% CI | |||
| Eg5 expression | ||||||||
| High versus low | 4.490 | <0.001∗ | 2.511 | 8.030 | 3.913 | <0.001∗ | 2.136 | 7.167 |
| Age (years) | ||||||||
| ≤60 versus >60 | 0.983 | 0.949 | 0.589 | 1.643 | ||||
| Gender | ||||||||
| Male versus female | 0755 | 0.260 | 0.463 | 1.323 | ||||
| Liver cirrhosis | ||||||||
| Yes versus no | 2.396 | 0.003∗ | 1.339 | 4.286 | 2.169 | 0.009∗ | 1.210 | 3.889 |
| Gross classification | ||||||||
| Solitary versus multiple | 2.292 | 0.007∗ | 1.254 | 4.188 | ||||
| Differentiation | ||||||||
| Well versus middle versus poor | 1.217 | 0.353 | 0.804 | 1.843 | ||||
| Hepatitis B viral infection | ||||||||
| Yes versus no | 1.489 | 0.438 | 0.544 | 4.072 | ||||
| Vascular invasion | ||||||||
| Yes versus no | 1.132 | 0.582 | 0.728 | 1.761 | ||||
| Tumor diameter (cm) | ||||||||
| <5 versus ≥5 | 1.287 | 0.277 | 0.816 | 2.029 | ||||
| TNM stage | ||||||||
| I versus II versus III | 1.604 | 0.011∗ | 1.112 | 2.313 | 1.524 | 0.025∗ | 1.053 | 2.206 |
| Preoperative α-fetoprotein (ng/ml) | ||||||||
| <20 versus ≥20 | 0.900 | 0.658 | 0.564 | 1.436 | ||||
∗ p < 0.05; HR: hazard ratio; 95% CI: 95% confidence interval.