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Expression of LDHA and GLUT1 in head and neck squamous cell carcinoma. (a) Correlation between expression of LDHA and GLUT1 mRNA in head and neck squamous cell carcinoma (n = 20). r s is the Spearman rank correlation coefficient. (b) Concentrations of lactic acid in tissues expressing lower and higher levels of LHDA (low, <3, n = 8; high, ≥3, n = 8) or GLUT1 (low, <4.2, n = 8; high, ≥4.2, n = 8). mRNA of these genes was measured by real‐time RT‐PCR. *P < 0.05 by Student's t‐test.
