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. 2017 Jun 20;15:12. doi: 10.1186/s12953-017-0120-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Liver model fabrication and characterization. a Experimental overview, (b) extracellular albumin (* p < 0.05, HM vs. 3DHL and 3DH), urea and glucose (* p < 0.05, unconditioned media (M) vs. conditioned media from 3DHL, 3DH and HM) levels for each culture condition after 72 h in culture