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. 2017 Jun 20;15:12. doi: 10.1186/s12953-017-0120-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Ketone bodies are produced by all three constructs. a Protein abundance ratios for proteins associated with ketogenesis based on the Top3 ion intensities (* p < 0.05 HM vs. 3DHL and 3DH). b Levels of the two main ketone bodies, acetoacetate and β-hydroxybutyrate, as measured by LC-MS/MS (* p < 0.05 HM vs. 3DHL and 3DH)