Table 1.
Proteins identified from conditioned (3DHL, 3DH) and unconditioned (FP) PEMs
| Description | UniProt ID | Unique peptides | 3DHL/FP (p-value) | 3DH/FP (p-value) |
|---|---|---|---|---|
| Collagen alpha-1 (I), Col1a1 | P02454 | 258 | 1.34 ± 0.18 (0.64) | 1.30 ± 0.06 (0.46) |
| Collagen alpha-2 (I), Col1a2 | P02466 | 198 | 1.06 ± 0.08 (0.72) | 1.08 ± 0.05 (0.59) |
| Collagen alpha-1 (III), Col3a1 | P13941 | 173 | 1.07 ± 0.06 (0.78) | 1.17 ± 0.13 (0.56) |
| Protein Col28a1 | D3ZN64 | 126 | 1.36 ± 0.08 (0.63) | 1.56 ± 0.21 (0.76) |
| Protein Col4a2 | F1M6Q3 | 125 | 1.43 ± 0.07 (0.58) | 1.35 ± 0.08 (0.49) |
| Collagen alpha-1 (II), Col2a1 | P05539 | 74 | 1.21 ± 0.02 (0.82) | 1.21 ± 0.14 (0.94) |
| Collagen alpha-1 (XI) | P20909 | 69 | 1.03 ± 0.18 (0.92) | 1.19 ± 0.49 (0.70) |
| Procollagen alpha-2 (XI), Col11a2 | Q6MGB2 | 61 | 1.50 ± 0.16 (0.67) | 1.58 ± 0.16 (0.44) |
| Procollagen alpha-1 (VII), Col7a1 | D3ZE04 | 54 | 0.71 ± 0.33 (0.63) | 0.80 ± 0.45 (0.69) |
| Protein Col4a5 | F1LUN5 | 50 | 1.26 ± 0.02 (0.76) | 1.24 ± 0.03 (0.62) |
| Protein Col5a2 | F1LQ00 | 44 | 0.66 ± 0.58 (0.66) | 0.40 ± 0.52 (1.00) |
| Protein Col4a1 | F1MA59 | 39 | 0.74 ± 0.18 (0.65) | 0.73 ± 0.23 (0.57) |
| Collagen alpha-1 (XXVII), Col27a1 | Q80ZF0 | 31 | 0.95 ± 0.17 (0.78) | 0.94 ± 0.02 (0.57) |
| Protein Col10a1 | A0A0G2K7A5 | 29 | 1.16 ± 0.05 (0.70) | 1.21 ± 0.01 (0.54) |
| Procollagen alpha-1 (V), Col5a1 | G3V763 | 15 | 1.47 ± 0.11 (0.63) | 1.53 ± 0.10 (0.44) |
| Protein Col14a1 | D3ZZT9 | 14 | 0.51 ± 0.09 (0.70) | 0.44 ± 0.06 (0.52) |
| Fibromodulin | P50609 | 5 | 0.32 ± 0.06 (0.95) | 0.29 ± 0.02 (0.83) |
Ratios were calculated based on the Top 3 method as described in the experimental section. Unique peptides represent the sum total of identifications across all samples