Figure 6.

MCC Is a Functional Target Gene of miR-4261 in HT29 Cells

(A) MCC siRNAs take effect in HT29 cells (n = 4). (B and C) MCC siRNAs abolish the suppressive effect of the miR-4261 inhibitor on cell proliferation (B) and G1/S phase transition of the cell cycle (C) in HT29 cells, as determined by EdU incorporation assay (n = 4; scale bars, 50 μm) and flow cytometry (n = 4). EdU is represented by green and DAPI by blue. *p < 0.05 versus control; ^#p < 0.05 versus miR-4261 inhibitor. Data are presented as mean ± SEM.